Meat Intake, Heterocyclic Amines, and Risk of Breast Cancer: A Case-Control Study in Uruguay1

نویسندگان

  • Eduardo De Stefani
  • Alvaro Ronco
  • Maria Mendilaharsu
  • Martha Guidobono
  • Hugo Deneo-Pellegrini
چکیده

To study the effects of meat intake, including heterocydic amine exposure, on the risk of breast cancer, we conducted a hospital-based case-control study involving 352 patients with breast cancer and 382 controls. A strong effect of red meat, total meat, beef, fried meat, and heterocydic amine exposure was found, after controffing for potential confounders. The odds ratio for the highest quartile of 2-amino-3-methylimidazo [4,5-fiquinoline exposure was 3.34 (95% confidence interval 1.85-6.02). According to these results, meat intake and chemicals formed during the cooking process appear to be strong risk factors in human breast carcinogenesis.

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منابع مشابه

Meat intake, heterocyclic amines, and risk of breast cancer: a case-control study in Uruguay.

To study the effects of meat intake, including heterocyclic amine exposure, on the risk of breast cancer, we conducted a hospital-based case-control study involving 352 patients with breast cancer and 382 controls. A strong effect of red meat, total meat, beef, fried meat, and heterocyclic amine exposure was found, after controlling for potential confounders. The odds ratio for the highest quar...

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تاریخ انتشار 2005